Application description

Table of Contents:

I. Neurocellular Anatomy

Neuron: Overview | Axon | Dendrite

Axonal Transport and Growth: Axoplasmic transport | Kinesin | Dynein | Myosin | Growth cone | Axon guidance

Synapse: Overview | Synaptic Vesicles | Exocytosis | Endocytosis | Synaptic plasticity | SNARE | Synaptobrevin | Synapsin | NSF

Glial cell: Overview | Astrocyte | Oligodendrocyte | Schwann cell | Myelin | Nodes of Ranvier | Multiple sclerosis

Cytoskeleton: Overview | Actin | Intermediate filament | Microtubule

II. Membranes And Transport

Membrane Structure: Overview | Fluid mosaic model | Detailed Structure

Lipids: Overview | Fatty acid | Fatty acid degradation | Fatty acid synthesis | Triglyceride | Waxes | Lipoprotein | Cholesterol

Membrane Components: Phospholipids | Sphingomyelin | Glycolipid | Glycocalix | Cholesterol | Antigen

Movement of Molecules: Diffusion | Osmosis | Electrochemical gradient

Passive transport: Passive transport | Facilitated diffusion | Ion channel

Blood-brain barrier: Overview | Tight junction | Cerebrospinal fluid

III. Ion Channels

Ion channels: Overview

Voltage-gated: Overview | Potassium channel | Sodium channel | BK channel | Inward-rectifier potassium ion channel | Resting channels | Calcium channel

Ligand-gated: Overview | NMDA receptor | AMPA receptor | Kainate receptor | Nicotinic acetylcholine receptor | Glycine receptor | GABA A receptor | GABA B receptor | GABA C receptor

Other ion channels: Cyclic nucleotide-gated | Stretch-activated | G-protein-gated | Light-gated

IV. Extracellular Signaling

Acetylcholine: Overview | Degradation by acetylcholinesterase | Receptors Overview | Nicotinic Receptors | Muscarinic Receptors | Muscarinic receptor agonist

Catecholamines: Overview | Epinephrine | Norepinephrine | Norepinephrine transporter | Dopamine | Dopamine transporter | Levodopa | Catecholamines breakdown | Adrenergic receptor | Dopamine receptor

Major dopamine pathways: Mesocortical pathway | Nigrostriatal pathway | Mesolimbic pathway | Tuberoinfundibular pathway

Serotonin: Overview | Serotonin transporter | Selective serotonin reuptake inhibitor | Receptors

Histamine: Overview | H1 receptor | H2 receptor | H3 receptor | H4 receptors | Antihistamine drugs

Glutamate: Overview | NMDA receptor | AMPA receptor | Kainate receptor | Glutamate transporter

Other Extracellular Signaling Molecules: Purines | Nitric oxide

Neuropeptides: Overview | Endorphin | Opioid receptor | Neuropeptide Y | Substance P | Neurokinin 1 | Cholecystokinin | Cholecystokinin receptor

Growth Factors: Overview | Granulocyte colony-stimulating factor | Nerve growth factor | Neurotrophin | Platelet-derived growth factor | Erythropoietin | Thrombopoietin | Myostatin | Basic fibroblast growth factor

Cell Adhesion: Overview | Families of cell adhesion molecules | Immunoglobulin Family | Integrins | Cadherin | Selectin

V. Intracellular Signalling

Intracellular signalling: Signal Amplification | Second messenger | Nuclear receptors | Calcium

Protein phosphorylation: Phosphorylation | Kinases | Serine/threonine-specific protein kinases | Phosphorylase kinase | Protein kinase A | Protein kinase C | Ca2+/calmodulin-dependent protein kinases | MAP kinases | Mos/Raf kinases | Tyrosine-specific protein kinases | Histidine-specific protein kinases | Phosphatase | Calmodulin

G Protein: Overview | G-protein-coupled receptors | GTPase

Phosphoinositides: Phosphatidylinositol | Phosphoinositide 3-kinase | Phosphatidylinositol (3,4)-bisphosphate | Phosphatidylinositol (3,5)-bisphosphate | Phosphatidylinositol (3,4,5)-trisphosphate

Lipophilic molecules: Diacylglycerol | Phospholipase | Inositol triphosphate | Prostaglandins | Ceramide | Cyclooxygenases | Eicosanoids

Cyclic Nucleotides: cAMP | Adenylate cyclase | cAMP-dependent protein kinase | cGMP | Guanylate cyclase | Phosphodiesterase

Techniques: CT | MRI | fMRI | PET | SPECT

Product Features:

• Fully illustrated.
• Clear and concise explanations.
• Difficult concepts are explained in simple terms.
• Navigate from Table of Contents or search for words or phrases.
• Multi-Platform Topaz capability (Topaz, Topaz, PC)
• Add Bookmarks
• Text annotation and mark-up
• Access the guide anytime, anywhere - at home, on the train, in the subway.
• Use your down time to prepare for an exam.
• Always have the guide available for a quick reference.
• Automatic synchronization between the Topaz and the desktop PC. You could read half of the book on the Topaz, then finish reading on the desktop. Annotations and drawings are also synchronized.

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